Periodontitis Disease and its Drug Delivery System
DOI:
https://doi.org/10.54060/pd.2023.2Keywords:
Periodontitis, drug delivery system, local drug delivery, sustained releaseAbstract
A persistent inflammatory condition known as periodontitis affects the structures supporting and around the teeth. The treatment of Periodontitis typically involves the use of systemic antibiotics, local drug delivery, and mechanical debridement. In recent years, drug delivery systems have gained popularity as a means of delivering therapeutic substances directly to the location of infection, improving the effectiveness of treatment while minimizing systemic side effects. Some of the most commonly used drug delivery systems for periodontitis include gels, films, and nanoparticles. These systems can be loaded with antibiotics, antiinflammatory agents, and growth factors, among other therapeutic agents, and can be designed to release the drug over a prolonged long enough to have ongoing therapeutic effects. Treatment of periodontitis by the use of drug delivery systems has shown promising results, with improved clinical outcomes and reduced systemic side effects. However, more study is required to assess these systems long-term safety and effectiveness as well as to improve their design and delivery. Keywords associated with drug delivery systems for periodontitis include local drug delivery, sus-tained release, nanoparticles, antibiotics, antiinflammatory agents, and growth factors.
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